Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29254199 | 0.86 | TSHR (0.56) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL29254196 | 0.86 | TSHR (0.56) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL5661624 | 0.84 | TSHR (0.61) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL13014394 | 0.83 | TSHR (0.61) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL10695276 | 0.82 | TSHR (0.59) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL10695280 | 0.82 | TSHR (0.59) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL8855359 | 0.82 | TSHR (0.55) | TSHRLOXL2IDO1KCNJ1KCNH2 | |
| SCHEMBL7358695 | 0.81 | GRM8 (0.56) | TSHRLOXL2KCNJ1KCNH2ANPEP | |
| SCHEMBL8092467 | 0.81 | GRM8 (0.56) | TSHRLOXL2KCNJ1KCNH2ANPEP | |
| SCHEMBL11375489 | 0.81 | ANPEP (0.51) | TSHRLOXL2IDO1KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018090-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF ZOLMITRIPTAN | MATRIX LABORATORIES LTD (IN) | 2008-02-14 | — | — | WO | disclosed |