Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439313 | 0.81 | HSD17B3 (0.41) | BCHEACHEMAPT | |
| SCHEMBL11375594 | 0.81 | KMT2A (0.40) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL11158189 | 0.80 | MEN1 (0.40) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL11377926 | 0.79 | KMT2A (0.40) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL11376111 | 0.79 | F10 (0.41) | BCHEACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL11377952 | 0.79 | MEN1 (0.45) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL11372430 | 0.79 | EGLN3 (0.47) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL11369729 | 0.78 | BCHE (0.38) | BCHEACHELMNA | |
| SCHEMBL11384247 | 0.77 | NR1I3 (0.42) | — | |
| SCHEMBL11376603 | 0.77 | F10 (0.41) | BCHEACHEMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289768-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-15 | — | — | US | disclosed |