Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376603 | 0.94 | F10 (0.41) | F10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11381139 | 0.91 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL11375869 | 0.84 | P2RX7 (0.42) | F10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11375594 | 0.81 | KMT2A (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL11153941 | 0.81 | ALDH1A1 (0.63) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL11372430 | 0.80 | EGLN3 (0.47) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL11158189 | 0.80 | MEN1 (0.40) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL11371213 | 0.80 | NOS1 (0.43) | ALDH1A1MAPTKDM4E | |
| SCHEMBL11377512 | 0.79 | KMT2A (0.44) | F10KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11375504 | 0.79 | BCHE (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289768-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-09-15 | — | — | US | disclosed |