Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HAT1 | O14929 | 2/20 | 0.60 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.60 |
| ▸ | TST | Q16762 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HBB | P68871 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30176235 | 0.85 | MEN1 (0.69) | TDP1MEN1USP2KMT2AKDM4E | |
| SCHEMBL11384276 | 0.82 | TDP1 (0.55) | TDP1MEN1USP2KMT2AKDM4E | |
| SCHEMBL11389527 | 0.79 | MEN1 (0.52) | TDP1MEN1USP2KMT2AKDM4E | |
| SCHEMBL11383191 | 0.78 | KDM4E (0.43) | TDP1MEN1USP2KMT2AKDM4E | |
| SCHEMBL15603809 | 0.78 | MEN1 (0.65) | TDP1MEN1USP2KMT2AKDM4E | |
| SCHEMBL16812918 | 0.78 | MEN1 (0.65) | TDP1MEN1USP2KMT2AKDM4E | |
| SCHEMBL15603799 | 0.77 | MEN1 (0.64) | TDP1MEN1USP2KMT2AKDM4E | |
| Riboflavin SCHEMBL9609755 | 0.75 | MEN1 (1.00) | TDP1MEN1USP2KMT2AKDM4E | |
| Riboflavin SCHEMBL12979917 | 0.75 | MEN1 (1.00) | TDP1MEN1USP2KMT2AKDM4E | |
| Riboflavin SCHEMBL7707 | 0.75 | MEN1 (1.00) | TDP1MEN1USP2KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252946-A | BACTERICIDES, FUNGICIDES, ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1981-02-24 | — | — | US | claimed |
| US-4252946-A | BACTERICIDES, FUNGICIDES, ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1981-02-24 | — | — | US | disclosed |
| US-4113859-A | ANTIBACTERIAL, ANTIPROTOZOAL, ANTIFUNGAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1978-09-12 | — | — | US | disclosed |