SCHEMBL16812918

SCHEMBL16812918

Cc1nc2c(=O)[nH]c(=O)nc-2n(CC(O)C(O)C(O)CO)c1C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.65
▸ KMT2A Q03164 6/20 0.65
▸ USP2 O75604 4/20 0.65
▸ HAT1 O14929 4/20 0.65
▸ RBBP7 Q16576 4/20 0.65
▸ HTT P42858 4/20 0.65
▸ KDM4E B2RXH2 3/20 0.65
▸ CASP1 P29466 2/20 0.65
▸ BRCA1 P38398 2/20 0.65
▸ RECQL P46063 2/20 0.65
▸ CASP7 P55210 2/20 0.65
▸ HSD17B10 Q99714 2/20 0.65
▸ TST Q16762 2/20 0.65
▸ MAPT P10636 2/20 0.65
▸ TDP1 Q9NUW8 2/20 0.65
▸ LMNA P02545 1/20 0.65
▸ HBB P68871 1/20 0.65
▸ ALDH1A1 P00352 1/20 0.65
▸ CYP1A2 P05177 1/20 0.65
▸ CYP3A4 P08684 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15603809 1.00 MEN1 (0.65) MEN1KMT2AUSP2HAT1RBBP7
SCHEMBL15604171 0.89 MEN1 (0.64) MEN1KMT2AUSP2HAT1RBBP7
SCHEMBL15603799 0.89 MEN1 (0.64) MEN1KMT2AUSP2HAT1RBBP7
SCHEMBL15603800 0.89 MEN1 (0.64) MEN1KMT2AUSP2HAT1RBBP7
Riboflavin SCHEMBL7706 0.79 MEN1 (1.00) MEN1KMT2AUSP2HAT1RBBP7
Riboflavin SCHEMBL2420598 0.79 MEN1 (1.00) MEN1KMT2AUSP2HAT1RBBP7
Riboflavin SCHEMBL13373926 0.79 MEN1 (1.00) MEN1KMT2AUSP2HAT1RBBP7
Riboflavin SCHEMBL12979917 0.79 MEN1 (1.00) MEN1KMT2AUSP2HAT1RBBP7
Riboflavin SCHEMBL7707 0.79 MEN1 (1.00) MEN1KMT2AUSP2HAT1RBBP7
Riboflavin SCHEMBL9609755 0.79 MEN1 (1.00) MEN1KMT2AUSP2HAT1RBBP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111595961-B Detection method of vitamin B2 related substances 南京海纳医药科技股份有限公司 2021-06-25 — — CN claimed
CN-111595961-A Detection method of vitamin B2 related substances 南京海纳医药科技股份有限公司 2020-08-28 — — CN claimed
CN-111595961-B Detection method of vitamin B2 related substances 南京海纳医药科技股份有限公司 2021-06-25 — — CN disclosed
CN-111595961-A Detection method of vitamin B2 related substances 南京海纳医药科技股份有限公司 2020-08-28 — — CN disclosed
US-10011602-B2 Immunological reagents and uses therefor THE UNIVERSITY OF MELBOURNE (AU) 2018-07-03 — — US disclosed
US-20150166542-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR THE UNIVERSITY OF MELBOURNE (AU) 2015-06-18 — — US disclosed
US-20150166542-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR THE UNIVERSITY OF MELBOURNE (AU) 2015-06-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166542-A1 IMMUNOLOGICAL REAGENTS AND USES THEREFOR CD81, MRGPRX1, MRGPRX2 MEN1 87/4885KMT2A 2569/4885USP2 4203/4885
US-10011602-B2 Immunological reagents and uses therefor CD81, MRGPRX1, MRGPRX2 MEN1 87/4885KMT2A 2569/4885USP2 4203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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