Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404213 | 0.86 | KMT2A (0.49) | MEN1POLBKMT2APTPN1CYP1A1 | |
| SCHEMBL11366270 | 0.79 | HPGD (0.43) | MEN1POLBKMT2APTPN1CYP1A2 | |
| SCHEMBL18271539 | 0.76 | CYP1A1 (0.44) | KMT2ACYP1A1CYP1B1CYP1A2ALDH1A1 | |
| SCHEMBL17382979 | 0.76 | ARSA (0.42) | CYP1A1CYP1B1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL31534638 | 0.76 | ARSA (0.42) | CYP1A1CYP1B1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL31591223 | 0.75 | POLB (0.51) | MEN1POLBKMT2APTPN1CYP1A1 | |
| SCHEMBL27356744 | 0.75 | MEN1 (0.42) | MEN1POLBKMT2APTPN1CYP1A1 | |
| SCHEMBL17382982 | 0.75 | ARSA (0.41) | CYP1A1CYP1B1CYP1A2ALDH1A1KDM4E | |
| SCHEMBL27355754 | 0.74 | KMT2A (0.44) | MEN1POLBKMT2APTPN1CYP1A1 | |
| SCHEMBL2247403 | 0.74 | MIF (0.44) | MEN1POLBKMT2APTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298532-A | INTERMEDIATES FOR MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1981-11-03 | — | — | US | disclosed |
| US-4260547-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4231965-A | CHEMICAL INTERMEDIATES FOR MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4154848-A | MICROBIOCIDES, BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4128659-A | 2-NITRO-3-PHENYL-BENZOFURANS | RIKER LABORATORIES, INC. (US) | 1978-12-05 | — | — | US | disclosed |