Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404213 | 0.85 | KMT2A (0.49) | HPGDMEN1KMT2APOLBKDM4E | |
| SCHEMBL11375864 | 0.79 | MEN1 (0.44) | HPGDMEN1KMT2APOLBKDM4E | |
| SCHEMBL11458495 | 0.77 | GSK3B (0.56) | POLBPTPN1GSK3BTNKSNPC1 | |
| SCHEMBL5788498 | 0.75 | HDAC8 (0.68) | POLBHDAC8HDAC6CYP1A2CYP2C9 | |
| SCHEMBL6378389 | 0.74 | MEN1 (0.50) | HPGDMEN1KMT2APOLBKDM4E | |
| SCHEMBL27356744 | 0.74 | MEN1 (0.42) | HPGDMEN1KMT2APOLBKDM4E | |
| SCHEMBL27355754 | 0.73 | KMT2A (0.44) | HPGDMEN1KMT2APOLBKDM4E | |
| SCHEMBL11815707 | 0.72 | TNKS (0.56) | HPGDPOLBKDM4EALDH1A1LMNA | |
| SCHEMBL10259329 | 0.72 | ALOX15 (0.50) | HPGDMEN1KMT2APOLBKDM4E | |
| SCHEMBL11510369 | 0.72 | MAOB (0.59) | HPGDMEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298532-A | INTERMEDIATES FOR MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1981-11-03 | — | — | US | disclosed |
| US-4260547-A | MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1981-04-07 | — | — | US | disclosed |
| US-4231965-A | CHEMICAL INTERMEDIATES FOR MICROBIOCIDES | RIKER LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4154848-A | MICROBIOCIDES, BACTERICIDES | RIKER LABORATORIES, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4128659-A | 2-NITRO-3-PHENYL-BENZOFURANS | RIKER LABORATORIES, INC. (US) | 1978-12-05 | — | — | US | disclosed |