Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268265 | 0.82 | JAK2 (0.62) | SMN1; SMN2TP53JAK2TYK2NPC1 | |
| SCHEMBL11366678 | 0.81 | TAAR1 (0.62) | TAAR1SMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL30318910 | 0.80 | TAAR1 (0.61) | TAAR1SMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL119685 | 0.80 | SMARCA2 (0.79) | TAAR1SMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL10344917 | 0.80 | TAAR1 (0.61) | TAAR1SMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL9828922 | 0.80 | SMARCA2 (0.69) | TAAR1SMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL10344696 | 0.80 | TAAR1 (0.61) | TAAR1SMN1; SMN2TP53EPHX1TSHR | |
| SCHEMBL14062132 | 0.79 | LMNA (0.62) | JAK2TYK2NPC1RAB9AMAPT | |
| SCHEMBL1269609 | 0.78 | EPHX2 (0.58) | SMN1; SMN2EPHX2JAK2TYK2NPC1 | |
| SCHEMBL1269674 | 0.78 | JAK2 (0.65) | SMN1; SMN2JAK2TYK2KDRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279639-A | N-(2-Substituted-4-pyridyl)ureas and thioureas as well as plant growth regulators containing same, and method for using compounds as plant growth regulators | Okamoto, Toshihiko (JP) | 1981-07-21 | — | — | US | disclosed |