Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679019 | 1.00 | TSHR (0.57) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL3889276 | 1.00 | TSHR (0.57) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL28219889 | 0.98 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL11491904 | 0.98 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL27627315 | 0.96 | TSHR (0.53) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1143951 | 0.92 | TSHR (0.50) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL4595511 | 0.92 | GAA (0.51) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL23824721 | 0.91 | TSHR (0.49) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28954178 | 0.91 | TSHR (0.49) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL28189103 | 0.91 | TSHR (0.73) | TSHRALDH1A1POLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2788 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119793223-A | Nanofiltration membrane, preparation method thereof and filtering device | 清华大学 | 2025-04-11 | — | — | CN | claimed |
| CN-114105910-B | Hydroxycarbamimidoyl phenylalanine derivative, pharmaceutical composition and application | 北京悦康科创医药科技股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| US-11926619-B2 | Certain pladienolide compounds and methods of use | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2024-03-12 | — | — | US | claimed |
| CN-113527270-B | Medical intermediate of PROTAC molecule targeting monoacylglycerol lipase, preparation method and application | 河南大学 | 2024-03-01 | — | — | CN | claimed |
| US-20230150924-A1 | NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND | CELLGENTEK CO., LTD. (KR) | 2023-05-18 | — | — | US | claimed |
| US-20230010299-A1 | HETEROCYCLIC TRPML1 AGONISTS | LIBRA THERAPEUTICS, INC. | 2023-01-12 | — | — | US | claimed |
| EP-4058145-A1 | HETEROCYCLIC TRPML1 AGONISTS | Libra Therapeutics, Inc. (US) | 2022-09-21 | — | — | EP | claimed |
| EP-4019495-A1 | NOVEL COMPOUND HAVING CANCER METASTASIS INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR INHIBITING CANCER METASTASIS AND INVASION OR TREATING COLORECTAL CANCER, COMPRISING COMPOUND | Cellgentek Co., Ltd (KR) | 2022-06-29 | — | — | EP | claimed |
| CN-110452130-B | Obovatol Mannich base derivative and preparation method and application thereof | 山西农业大学 | 2022-03-01 | — | — | CN | claimed |
| US-11123683-B2 | Carbon dioxide absorbent and apparatus of separating and recovering carbon dioxide | KABUSHIKI KAISHA TOSHIBA (JP) | 2021-09-21 | — | — | US | claimed |
| US-4737494-A | 2-YLIDENE AMMONIUM COMPOUNDS USED IN TREATING LIVER DISEASES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-12 | — | — | US | claimed |
| EP-0188805-A1 | 1,3-Dithiole derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-07-30 | — | — | EP | claimed |
| EP-0020303-B1 | GUANIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | claimed |
| US-4398940-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1983-08-16 | — | — | US | claimed |
| US-4385055-A | 2-Acetyl-and 2-propionylpyridine thiosemicarbazones as antimalarials | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1983-05-24 | — | — | US | claimed |
| US-4348389-A | Quinoxaline adducts useful as anthelmintics | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1982-09-07 | — | — | US | claimed |
| US-4323677-A | LEGUME PLANT GROWTH REGULATOR | MONSANTO COMPANY (US) | 1982-04-06 | — | — | US | claimed |
| EP-0028083-A1 | Derivatives of clavulanic acid, a process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-05-06 | — | — | EP | claimed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | claimed |
| US-3939268-A | 2,4-Diamino substituted pyridol(3,2-d)pyrimidine as antithrombotic agents | BOEHRINGER INGELHEIM GMBH (DT) | 1976-02-17 | — | — | US | claimed |