Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679019 | 1.00 | TSHR (0.57) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL113765 | 1.00 | TSHR (0.57) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL28219889 | 0.98 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL11491904 | 0.98 | TSHR (0.55) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL27627315 | 0.96 | TSHR (0.53) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| SCHEMBL1143951 | 0.92 | TSHR (0.50) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL4595511 | 0.92 | GAA (0.51) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL23824721 | 0.91 | TSHR (0.49) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28954178 | 0.91 | TSHR (0.49) | TSHRALDH1A1POLBSMN1; SMN2HTT | |
| N-(Ethoxycarbonyl)Piperazine SCHEMBL28189103 | 0.91 | TSHR (0.73) | TSHRALDH1A1POLBSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763438-A | ANTIVIRAL AGENTS | SEIKAGAKU CORPORATION (JP) | 1998-06-09 | — | — | US | claimed |
| EP-0765865-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1997-04-02 | — | — | EP | claimed |
| US-20170014468-A1 | METHODS OF USE FOR THERAPEUTICS TARGETING THE PATHOGEN PORPHYROMONAS GINGIVALIS | Cortexyme, Inc. | 2017-01-19 | — | — | US | disclosed |
| EP-1333024-B1 | PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF | UNIV KYUSHU NAT UNIV CORP (JP) | 2009-01-07 | — | — | EP | disclosed |
| US-6951843-B2 | Peptide derivatives and their pharmaceutically acceptable salts, thereof, processes for preparation of both and use thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2005-10-04 | — | — | US | disclosed |
| EP-1333024-A1 | PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, PROCESSES FOR PREPARATION OF BOTH, AND USE THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-20030087828-A1 | Peptide derivatives and pharmaceutically acceptable salts, thereof, processes for preparation of both, and use thereof | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2003-05-08 | — | — | US | disclosed |
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5763438-A | ANTIVIRAL AGENTS | SEIKAGAKU CORPORATION (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0765865-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1997-04-02 | — | — | EP | disclosed |
| WO-1996033723-A2 | USE OF BENZAMIDE DERIVATIVES FOR TREATING AND/OR PREVENTING MENIERE'S SYNDROME AND MOTION SICKNESS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087828-A1 | Peptide derivatives and pharmaceutically acceptable salts, thereof, processes for preparation of both, and use thereof | NGLY1, DOHH, VIP | TSHR 1717/4885ALDH1A1 2677/4885POLB 2512/4885 |
| US-20170014468-A1 | METHODS OF USE FOR THERAPEUTICS TARGETING THE PATHOGEN PORPHYROMONAS GINGIVALIS | AGER, CD38, APP | TSHR 1847/4885ALDH1A1 3865/4885POLB 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.