Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.74 |
| ▸ | BCHE | P06276 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | ATP4A | P20648 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | ATP4B | P51164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361485 | 0.92 | ACHE (0.87) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11208099 | 0.85 | ACHE (1.00) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11360954 | 0.85 | ACHE (0.68) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11365282 | 0.82 | ACHE (0.68) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11368524 | 0.80 | ACHE (0.90) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11368521 | 0.80 | ACHE (0.90) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11363130 | 0.79 | ACHE (0.81) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL11078855 | 0.78 | ACHE (0.83) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL2593630 | 0.78 | ACHE (0.80) | ACHEBCHEMEN1SLC22A1ABCB11 | |
| SCHEMBL10358390 | 0.78 | ACHE (0.96) | ACHEBCHEPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4279819-A | GASTROINTESTINAL DISORDERS | ALLEN & HANBURYS LTD. (GB) | 1981-07-21 | — | — | US | disclosed |
| US-4255440-A | ANTIALLERGENS, ANTIULCER AGENTS | ALLEN & HANBURYS LIMITED (GB) | 1981-03-10 | — | — | US | disclosed |
| US-4169855-A | ANTIHISTAMINES, ANTISECRETORY AGENTS | Allen & Hansbury, Limited (GB) | 1979-10-02 | — | — | US | disclosed |
| US-4128658-A | HISTAMINE ANTAGONISTS | ALLEN & HANBURYS LIMITED (GB) | 1978-12-05 | — | — | US | disclosed |