Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | CDC25C | P30307 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11132823 | 0.91 | KCNH2 (0.57) | KCNH2MAPTTSHRCRHBPCRHR2 | |
| SCHEMBL4321265 | 0.86 | KCNH2 (0.64) | KCNH2MAPTTSHRCRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL11232654 | 0.84 | KCNH2 (0.62) | KCNH2MAPTTSHRCRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL11441815 | 0.83 | KCNH2 (0.65) | KCNH2MAPTTSHRCRHBPCRHR2 | |
| SCHEMBL777298 | 0.81 | KCNH2 (0.60) | KCNH2TSHRCRHBPCRHR2SIGMAR1 | |
| SCHEMBL13897015 | 0.78 | KCNH2 (0.72) | KCNH2MAPTMEN1KMT2ATSHR | |
| Oxalic Acid SCHEMBL11231282 | 0.78 | KCNH2 (0.59) | KCNH2MEN1KMT2ATSHRCRHBP | |
| Oxalic Acid SCHEMBL11231251 | 0.78 | KCNH2 (0.59) | KCNH2MEN1KMT2ATSHRCRHBP | |
| SCHEMBL11380653 | 0.78 | SIGMAR1 (0.59) | KCNH2SIGMAR1POLB | |
| SCHEMBL11387795 | 0.76 | BCL2L1 (0.50) | KCNH2TSHRSIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285961-A | MICROBIOCIDES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-08-25 | — | — | US | disclosed |