SCHEMBL11378583

SCHEMBL11378583

COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2C)CC1

nearest known ligand 0.76

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.76
POLB P06746 1/20 0.76
DRD4 P21917 3/20 0.63
DRD2 P14416 2/20 0.63
HTR1A P08908 5/20 0.60
ADRA1D P25100 1/20 0.59
ADRA1A P35348 1/20 0.59
ADRA1B P35368 1/20 0.59
DRD3 P35462 1/20 0.59
MEN1 O00255 1/20 0.57
TSHR P16473 1/20 0.57
KMT2A Q03164 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11757536 0.91 ALDH1A1 (0.74) ALDH1A1POLBDRD4DRD2HTR1A
Hydrochloric Acid SCHEMBL11844275 0.90 ALDH1A1 (0.72) ALDH1A1POLBDRD4DRD2HTR1A
SCHEMBL11605903 0.90 ALDH1A1 (0.72) ALDH1A1POLBDRD4DRD2HTR1A
SCHEMBL11476236 0.90 ALDH1A1 (0.72) ALDH1A1POLBDRD4DRD2HTR1A
SCHEMBL11835888 0.87 ALDH1A1 (0.71) ALDH1A1POLBDRD4DRD2HTR1A
SCHEMBL11825301 0.86 ALDH1A1 (0.67) ALDH1A1POLBDRD4DRD2HTR1A
SCHEMBL11827046 0.86 ALDH1A1 (0.67) ALDH1A1POLBDRD4DRD2HTR1A
Fluanisone SCHEMBL145054 0.86 ALDH1A1 (1.00) ALDH1A1POLBDRD4DRD2HTR1A
SCHEMBL11606079 0.85 ALDH1A1 (0.66) ALDH1A1POLBDRD4DRD2HTR1A
Fluanisone SCHEMBL29389457 0.85 ALDH1A1 (0.98) ALDH1A1POLBDRD4DRD2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4303663-A ANALGESICS, NEUROLEPTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-12-01 US disclosed
US-4039670-A BUTYROPHENONE COMPOUNDS AS PSYCHOTROPICS SUMITOMO CHEMICAL CO., LTD. (JA) 1977-08-02 US disclosed