Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386196 | 0.91 | KDM4E (0.51) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL11372008 | 0.86 | KDM4E (0.51) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL11380712 | 0.85 | KDM4E (0.70) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL11177263 | 0.81 | KDM4E (0.45) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL11374450 | 0.79 | CHRM2 (0.52) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL11347453 | 0.78 | HDAC3 (0.65) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL11395534 | 0.76 | CHRM2 (0.60) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL13432191 | 0.76 | PRF1 (0.44) | KDM4EALOX15TSHRSIRT1HDAC6 | |
| SCHEMBL11383254 | 0.74 | KMT2A (0.46) | KDM4EALOX15TSHRKMT2AMEN1 | |
| SCHEMBL6411213 | 0.73 | TP53 (0.59) | KDM4EALOX15TSHRSIRT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006587-B1 | SULFONYL UREAS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-11 | — | — | EP | disclosed |
| US-4282239-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-04 | — | — | US | disclosed |