Cyclohexane

Cyclohexane

SCHEMBL11380245

C1CCCCC1.C1CCOC1.CO

nearest known ligand 0.67

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.67
TTR P02766 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL1534171 1.00 ALDH1A1 (0.67) ALDH1A1TTRTSHR
Methyl Alcohol SCHEMBL9304289 1.00
Tetrahydrofuran SCHEMBL49157 0.96
Tetrahydrofuran SCHEMBL18167417 0.96 ALDH1A1 (0.73) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL5244965 0.96 ALDH1A1 (0.73) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL3181441 0.96 ALDH1A1 (0.73) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL1708038 0.96 ALDH1A1 (0.73) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL1615823 0.92
Dioxane SCHEMBL28216951 0.92 ALDH1A1 (0.67) ALDH1A1TTRTSHR
Tetrahydrofuran SCHEMBL11075183 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4287302-A Microbiological modification of antibiotic A23187 esters ELI LILLY AND COMPANY (US) 1981-09-01 US disclosed
US-4247703-A METHYL ESTER OF THE 16-HYDROXY-, 16-HYDROXY-N-DEMETHYL-, AND N-DEMETHYL- DERIVATIVES ELI LILLY AND COMPANY (US) 1981-01-27 US disclosed