Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | RAB9A | P51151 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PDXK | O00764 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183097 | 0.78 | PDXK (0.36) | SMN1; SMN2LMNAGAAHTTKMT2A | |
| SCHEMBL18335168 | 0.78 | PLAU (0.42) | LMNAPLAUHTTKMT2AMAPT | |
| SCHEMBL30821436 | 0.78 | PDXK (0.36) | HSD17B10PDXK | |
| SCHEMBL17688337 | 0.78 | PLAU (0.42) | PLAUPDXK | |
| SCHEMBL30224739 | 0.78 | MAPT (0.32) | L3MBTL1HTTHSD17B10MAPTALDH1A1 | |
| SCHEMBL29267294 | 0.78 | CYP3A4 (0.36) | TSHRALDH1A1 | |
| SCHEMBL27223973 | 0.78 | PDXK (0.36) | HSD17B10PDXK | |
| SCHEMBL17688294 | 0.78 | IDO1 (0.35) | SMN1; SMN2TSHRPLAUMAPK1HSD17B10 | |
| SCHEMBL16512928 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL15049620 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNACYP2C9TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071629-B2 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | disclosed |
| US-7932396-B2 | 2-pyridinylcycloalkylbenzamide derivatives and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2011-04-26 | — | — | US | disclosed |
| EP-1885712-B1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE AG (DE) | 2011-02-23 | — | — | EP | disclosed |
| US-20090099234-A1 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | BAYER CROPSCIENCE AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090076096-A1 | 2-Pyridinylcycloalkylbenzamide derivatives and their use as fungicides | BAYER CROPSCIENCE AG (DE) | 2009-03-19 | — | — | US | disclosed |
| EP-1885712-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2008-02-13 | — | — | EP | disclosed |
| EP-1885698-A1 | 2-PYRIDINYLCYCLOALKYLBENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006122952-A1 | 2-PYRIDINYLCYCLOALKYLBENZAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006122955-A1 | NEW 2-PYRIDINYLCYCLOALKYLCARBOXAMIDE DERIVATIVES AS FUNGICIDES. | BAYER CROPSCIENCE SA (FR) | 2006-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076096-A1 | 2-Pyridinylcycloalkylbenzamide derivatives and their use as fungicides | CYP1A2, CYP4B1, CYP4F2 | SMN1; SMN2 3198/4885LMNA 2925/4885CYP2C9 16/4885 |
| US-20090099234-A1 | 2-pyridinylcycloalkylcarboxamide derivatives as fungicides | CYP1A2, CYP4F2, CYP4F12 | SMN1; SMN2 2634/4885LMNA 2965/4885CYP2C9 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.