Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135664 | 0.80 | LPAR1 (0.65) | LPAR1LPAR5MAPK14XIAPEZH2 | |
| SCHEMBL29784341 | 0.80 | LPAR1 (0.65) | LPAR1LPAR5MAPK14XIAPEZH2 | |
| SCHEMBL7248002 | 0.80 | CES1 (0.67) | CES1MAPK14MLYCDPARP10 | |
| SCHEMBL11511159 | 0.79 | MAPT (0.60) | LPAR1LPAR5MAPK14XIAPEZH2 | |
| SCHEMBL27480252 | 0.79 | PARP10 (0.66) | LPAR1LPAR5MAPK14XIAPEZH2 | |
| SCHEMBL27874065 | 0.79 | SRD5A2 (0.56) | LPAR1LPAR5MAPK14XIAPEZH2 | |
| SCHEMBL7176453 | 0.77 | DPP4 (0.53) | LPAR1LPAR5MAPK14XIAPAR | |
| SCHEMBL27449133 | 0.76 | MAPT (0.56) | LPAR1LPAR5MAPK14XIAPEZH2 | |
| SCHEMBL11380431 | 0.75 | MAPT (0.56) | PNLIP | |
| SCHEMBL10573534 | 0.75 | MAPK14 (0.52) | LPAR1LPAR5MAPK14XIAPEZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288453-A | A-(1-PHENYL-2,2,2-TRIFLUOROETHOXY (OR -ETHYLTHIO))ALKANOIC ACIDS USEFUL AS ANTICHOLESTEROL AND ANTILIPEMIC AGENTS | SCIENCE UNION ET CIE (FR) | 1981-09-08 | — | — | US | disclosed |