Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.53 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.52 |
| ▸ | ESRRA | P11474 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875079 | 0.87 | MAPT (0.56) | MAPTHPGDRAB9AMAOBMAOA | |
| SCHEMBL3135664 | 0.84 | LPAR1 (0.65) | HPGDXIAPLPAR1LPAR5MAPK14 | |
| SCHEMBL29784341 | 0.84 | LPAR1 (0.65) | HPGDXIAPLPAR1LPAR5MAPK14 | |
| SCHEMBL27449133 | 0.83 | MAPT (0.56) | MAPTRAB9AXIAPLPAR1LPAR5 | |
| SCHEMBL27480252 | 0.83 | PARP10 (0.66) | XIAPLPAR1LPAR5MAPK14EZH2 | |
| SCHEMBL27874065 | 0.83 | SRD5A2 (0.56) | XIAPLPAR1LPAR5MAPK14EZH2 | |
| SCHEMBL9861909 | 0.82 | MAPT (0.64) | MAPTHPGDRAB9AMAOBMAOA | |
| SCHEMBL11833791 | 0.82 | MEN1 (0.55) | RAB9AMAOBMAOAXIAPESRRA | |
| SCHEMBL7176453 | 0.81 | DPP4 (0.53) | MAPTHPGDXIAPLPAR1LPAR5 | |
| SCHEMBL10825738 | 0.81 | ESRRA (0.68) | MAPTHPGDRAB9AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |
| US-4136200-A | PHENYLBUTANOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4049823-A | Phenylbutanol derivatives and compositions containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-20 | — | — | US | disclosed |