SCHEMBL11380824

SCHEMBL11380824

CC1OC=CC1OCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.41
TSHR P16473 2/20 0.41
MAPT P10636 1/20 0.38
PDPK1 O15530 1/20 0.36
MTOR P42345 1/20 0.36
CCKBR P32239 1/20 0.35
IDO1 P14902 1/20 0.35
CYP1A2 P05177 1/20 0.35
CTSL P07711 1/20 0.35
CTSB P07858 1/20 0.35
CTSK P43235 1/20 0.35
OPRM1 P35372 2/20 0.35
OPRL1 P41146 2/20 0.35
AGXT P21549 1/20 0.34
ALDH1A1 P00352 2/20 0.34
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13869160 0.90 CYP2C19 (0.36) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL17265241 0.90 CYP2C19 (0.36) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL13869157 0.89 PDPK1 (0.40) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL13869159 0.89 PDPK1 (0.40) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL28345301 0.89 PDPK1 (0.40) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL15366444 0.87 FUCA1 (0.42) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL17265333 0.87 FUCA1 (0.42) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL15366445 0.87 FUCA1 (0.42) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL17265338 0.86 CYP2C19 (0.40) CYP2C19TSHRMAPTPDPK1MTOR
SCHEMBL12573460 0.83 CYP2C19 (0.48) CYP2C19TSHRMAPTPDPK1MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30574-E PREEMERGENT AND POSTEMERGENT SHELL OIL COMPANY (US) 1981-04-14 US disclosed