Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376576 | 0.83 | MEN1 (0.58) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL11371011 | 0.80 | L3MBTL1 (0.63) | RAB9AMAPTSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL6179431 | 0.80 | AKR1C3 (0.74) | AKR1C3AKR1C2RAB9AMAPTNPC1 | |
| SCHEMBL11372349 | 0.77 | MAPK1 (0.56) | AKR1C3AKR1C2RAB9AMAPTNPC1 | |
| SCHEMBL11369996 | 0.77 | MAPK1 (0.51) | RAB9AMAPTNPC1SMN1; SMN2MAPK1 | |
| SCHEMBL7950731 | 0.76 | AKR1C3 (0.65) | AKR1C3AKR1C2RAB9AMAPTNPC1 | |
| SCHEMBL26906360 | 0.76 | MAPT (0.75) | AKR1C3AKR1C2RAB9AMAPTNPC1 | |
| SCHEMBL19047094 | 0.76 | AKR1C3 (0.57) | AKR1C3AKR1C2RAB9AMAPTNPC1 | |
| SCHEMBL31220866 | 0.74 | MEN1 (0.68) | AKR1C3AKR1C2RAB9AMAPTNPC1 | |
| SCHEMBL430629 | 0.74 | MAPT (0.59) | AKR1C3AKR1C2RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293566-A | FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4183949-A | Pesticidally active 1-arylamino-2,4-dinitronaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |