Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 14/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376509 | 0.96 | HTR4 (0.67) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| Bromomethane SCHEMBL11378543 | 0.94 | HTR4 (0.65) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL11387050 | 0.93 | HTR4 (0.72) | HTR4MEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL11382294 | 0.90 | HTR4 (0.62) | HTR4 | |
| SCHEMBL11376674 | 0.85 | HTR4 (0.69) | HTR4 | |
| SCHEMBL11380863 | 0.84 | HTR4 (0.57) | HTR4HTR3A | |
| SCHEMBL11538644 | 0.83 | HTR4 (0.66) | HTR4CYP3A4HTR3A | |
| SCHEMBL11376663 | 0.83 | HTR4 (0.59) | HTR4 | |
| SCHEMBL11379701 | 0.82 | HTR4 (0.58) | HTR4MEN1CYP2D6KMT2ACYP2C9 | |
| Bromomethane SCHEMBL11381329 | 0.80 | HTR4 (0.56) | HTR4KMT2AHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4267175-A | FOR USE AS AN ANTIEMETIC, AND TREATMENT FOR GASTROINTESTINAL DISORDERS | BEECHAM GROUP LIMITED (GB) | 1981-05-12 | — | — | US | disclosed |