Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 3/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | POU5F1 | Q01860 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | SLC47A2 | Q86VL8 | 2/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.40 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL11385714 | 0.93 | SLC22A2 (0.36) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL7119649 | 0.90 | HRH2 (0.42) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL972 | 0.90 | SLC22A2 (0.43) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL1163669 | 0.90 | SLC22A2 (0.43) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL19555077 | 0.89 | HRH2 (0.43) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL1863196 | 0.89 | SLC22A2 (0.43) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11382766 | 0.88 | LMNA (0.39) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL22127094 | 0.88 | SLC22A2 (0.42) | HRH2SLC22A2CA12SLC22A3CA1 | |
| Famotidine SCHEMBL18335716 | 0.86 | CA12 (0.39) | HRH2SLC22A2CA12SLC22A3CA1 | |
| SCHEMBL11393019 | 0.86 | LMNA (0.37) | HRH2SLC22A2CA12SLC22A3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283408-A | Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | claimed |
| WO-2021183259-A1 | FAMOTIDINE AND FAMOTIDINE ANALOGS FOR CORONA VIRUS TREATMENT | Nanopharmaceutics, Inc. (US) | 2021-09-16 | — | — | WO | disclosed |
| US-4283408-A | Guanidinothiazole compounds, process for preparation and gastric inhibiting compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-08-11 | — | — | US | disclosed |