Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707712 | 0.86 | KDM4E (0.61) | KDM4ECYP1A2CYP2C19TNKS2GRM5 | |
| SCHEMBL13429182 | 0.85 | MEN1 (0.58) | KDM4ECYP1A2CYP2C19TNKS2GRM5 | |
| SCHEMBL24237032 | 0.83 | KDM4E (0.61) | KDM4ECYP1A2CYP2C19TNKS2GRM5 | |
| SCHEMBL31664571 | 0.81 | TNKS2 (0.61) | KDM4ECYP1A2CYP2C19TNKS2KMT2A | |
| SCHEMBL2799080 | 0.81 | TNKS2 (0.61) | KDM4ECYP1A2CYP2C19TNKS2KMT2A | |
| SCHEMBL2796820 | 0.81 | CTSV (0.56) | KDM4ECYP1A2CYP2C19TNKS2GRM5 | |
| SCHEMBL31240336 | 0.80 | CYP1A2 (0.47) | KDM4ECYP1A2CYP2C19TNKS2GRM5 | |
| SCHEMBL5721982 | 0.78 | KDM4E (0.55) | KDM4ECYP1A2CYP2C19TNKS2KMT2A | |
| SCHEMBL9029582 | 0.77 | CYP1A2 (0.56) | KDM4ECYP1A2CYP2C19TNKS2GRM5 | |
| SCHEMBL24523099 | 0.77 | KDM4E (0.57) | KDM4ECYP1A2CYP2C19GRM5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | disclosed |