Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 8/20 | 0.72 |
| ▸ | HTR2A | P28223 | 7/20 | 0.72 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.51 |
| ▸ | SCN1A | P35498 | 4/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | THPO | P40225 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | HRH2 | P25021 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1802493 | 0.85 | HRH1 (1.00) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL11379245 | 0.85 | HTR2A (0.50) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL11382925 | 0.83 | SIGMAR1 (0.60) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL11379483 | 0.83 | HRH1 (0.49) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11383046 | 0.83 | HRH1 (0.95) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| Tolpropamine SCHEMBL29300 | 0.80 | HRH1 (0.81) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL11396852 | 0.80 | HRH1 (0.62) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL11387932 | 0.79 | HTR2A (0.53) | HRH1HTR2ASLC6A4CHRNA7SIGMAR1 | |
| SCHEMBL11390029 | 0.79 | HTR2A (0.53) | HRH1HTR2ASLC6A4CHRNA7LMNA | |
| SCHEMBL10778672 | 0.79 | HTR2A (0.78) | HRH1HTR2ACHRM2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285961-A | MICROBIOCIDES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-08-25 | — | — | US | disclosed |