Beta-Caryophyllene

Beta-Caryophyllene

SCHEMBL113830

C=C1CC/C=C(\C)CC[C@@H]2[C@@H]1CC2(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 1.00
PPARA Q07869 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
CYP3A4 P08684 7/20 0.50
FTH1 P02794 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
USP2 O75604 1/20 0.45
PTGS1 P23219 1/20 0.41
TAS2R46 P59540 2/20 0.38
PKM P14618 2/20 0.38
RECQL P46063 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TERT O14746 1/20 0.38
NLRP3 Q96P20 2/20 0.36
ALDH1A1 P00352 2/20 0.36
NFKB1 P19838 2/20 0.36
CASP1 P29466 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-Caryophyllene SCHEMBL4195147 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL3505514 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Caryophyllene SCHEMBL4355327 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL4195140 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL4195149 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL24774027 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL1866747 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Caryophyllene SCHEMBL310637 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL22607973 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4
Beta-Caryophyllene SCHEMBL29380416 1.00 CNR2 (1.00) CNR2PPARAMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19326 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746708-A1 VOC COMPOSITION AND MINERAL CARRIER THEREOF Agriodor (FR) 2026-05-27 EP claimed
US-20260137708-A1 TOPICAL FORMUATIONS AND INSTILLATES, KITS, AND METHODS FOR TREATING INTEGUMENTARY WOUNDS, AND USES THEREOF VINSAN THERAPEUTICS INC (CA) 2026-05-21 US claimed
CN-117502441-B Attractant, insecticidal gel bait and brushing type insecticidal agent 中山榄菊日化实业有限公司 2026-05-19 CN claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122042875-A Method for directionally extracting sweet smell characteristic mark components from Shennong chrysanthemum 北京林业大学 2026-05-15 CN claimed
CN-122031379-A Fluorine Lei Lana-moxidectin nano drop containing penetration enhancer and preparation method thereof 广州白云山宝神动物保健品有限公司 2026-05-15 CN claimed
WO-2026097682-A1 GREEN AND EFFICIENT METHOD AND APPARATUS FOR HYDRATING CARYOPHYLLENE 南京安立格有限公司 2026-05-15 WO claimed
EP-4514146-B1 A COMBINATION FOR USE IN THE PREPARATION OF A DRINKABLE FOAMING OR FOAMABLE LIQUID, A DEVICE AND A METHOD FOR PREPARING AND DISPENSING A DRINKABLE FOAMING OR FOAMABLE LIQUID BAR ON B V (BE) 2026-05-13 EP claimed
CN-122004079-A Green prevention and control method for longicorn 上海市绿化管理指导站 2026-05-12 CN claimed
CN-122024905-A Method for screening essential oil key pleasant components based on bimodal neural imaging and application 上海应用技术大学 2026-05-12 CN claimed
US-4190460-A Sulfur plasticization with olefins SUNTECH, INC. (US) 1980-02-26 US claimed
US-4103036-A Flavoring with derivatives of 1-acetyl-3,3-dimethylcyclohexane, and processes for using same and processes for preparing said 1-acetyl-3,3-dimethylcyclohexane derivatives INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-07-25 US claimed
US-4093752-A FOODSTUFFS, CHEWING GUM, TOOTHPASTE, MEDICINES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-06 US claimed
US-4089986-A FOODS, TOOTHPASTE, CHEWING GUM, DRUGS, PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-05-16 US claimed
US-4084009-A 4-HYDROXY-2,4,6,6-TETRAMETHYLCYCLOHEX-2-ENE-1-ONE, ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-04-11 US claimed
US-4076854-A ADJUVANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-02-28 US claimed
US-4068012-A FLAVORS, PERFUMES, TOBACCO INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-01-10 US claimed
US-4053657-A FOODS AND FLAVOR USE OF 1-(3,3-DIMETHYL-2-NORBORNYL-2-PROPANONE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US claimed
US-4014350-A CARYOPHYLLENE EPOXIDE AND ITS ALCOHOLS; FLAVORINGS FOR TOBACCO, FOODSTUFFS AND DRUGS FIRMENICH S.A. (CH) 1977-03-29 US claimed
US-4000329-A Flavoring compositions and foods containing one or more alkyl side chain methyl substituted or unsubstituted 2,2,6-trimethyl-1-cyclohexen-1-vinyl alkanoates INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-28 US claimed