Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365956 | 0.91 | ADRB2 (0.44) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| SCHEMBL11377591 | 0.90 | ADRB2 (0.45) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| SCHEMBL11372453 | 0.90 | ADRB2 (0.46) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| SCHEMBL11376096 | 0.89 | ADRB2 (0.46) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| SCHEMBL11373293 | 0.89 | ADRB2 (0.46) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| Hydrochloric Acid SCHEMBL11365766 | 0.89 | ADRB2 (0.46) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| SCHEMBL11371511 | 0.89 | ADRB3 (0.43) | ADRB2ADRB1ADRB3DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL11374289 | 0.88 | ADRB2 (0.45) | ADRB2ADRB1ADRB3ADRA2BDRD2 | |
| SCHEMBL11367824 | 0.88 | ADRB2 (0.42) | ADRB2ADRB1ADRB3ADRA2BADRA2A | |
| SCHEMBL11375196 | 0.87 | ADRB2 (0.49) | ADRB2ADRB1ADRB3ADRA2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304790-A | 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof | SCHERING CORPORATION (US) | 1981-12-08 | — | — | US | claimed |
| US-4304790-A | 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof | SCHERING CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |