Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.62 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.49 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15008043 | 0.84 | MAPK14 (0.54) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL11379662 | 0.83 | SCN5A (0.59) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL2538610 | 0.82 | SCN5A (0.51) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL11474506 | 0.81 | SCN5A (0.58) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL11476887 | 0.81 | SCN5A (0.58) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL11486274 | 0.81 | SCN5A (0.58) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL19806542 | 0.78 | MAPK14 (0.56) | MAPK14SCN5ATGFBR1DNMT1PIK3CA | |
| SCHEMBL11475951 | 0.77 | SCN5A (0.57) | MAPK14SCN5ATGFBR1DNMT1NPC1 | |
| SCHEMBL11491065 | 0.77 | SCN5A (0.66) | MAPK14SCN5ADNMT1PIK3CAALDH1A3 | |
| SCHEMBL2538823 | 0.77 | SCN5A (0.50) | MAPK14SCN5ATGFBR1DNMT1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4244953-A | Substituted 6-phenyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4209626-A | Substituted 6-phenyl-1,2,4-triazolo[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |