Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 4/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL252922 | 0.84 | PIK3CG (0.47) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 | |
| SCHEMBL11379662 | 0.83 | SCN5A (0.59) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 | |
| SCHEMBL11474506 | 0.81 | SCN5A (0.58) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 | |
| SCHEMBL11384331 | 0.81 | MAPK14 (0.64) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 | |
| SCHEMBL11476887 | 0.81 | SCN5A (0.58) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 | |
| SCHEMBL11475951 | 0.77 | SCN5A (0.57) | SCN5ADNMT1MAPK14TGFBR1NPC1 | |
| SCHEMBL11491065 | 0.77 | SCN5A (0.66) | SCN5ADNMT1MAPK14NPC1RAB9A | |
| SCHEMBL11383420 | 0.75 | SCN5A (0.51) | SCN5ADNMT1ALDH1A1MAPK14NPC1 | |
| SCHEMBL937590 | 0.75 | SCN5A (0.62) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 | |
| SCHEMBL936850 | 0.74 | SCN5A (1.00) | SCN5ADNMT1ALDH1A1MAPK14TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209626-A | Substituted 6-phenyl-1,2,4-triazolo[4,3-a]pyridines | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |