Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375444 | 0.83 | KCNA3 (0.69) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL11389662 | 0.81 | KCNA3 (0.74) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL11385254 | 0.79 | KCNA3 (0.77) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL18026627 | 0.79 | KCNA3 (0.64) | KCNA3SMN1; SMN2HPGDLMNABRD4 | |
| SCHEMBL11377494 | 0.78 | KCNA3 (0.56) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL16364135 | 0.78 | KCNA3 (0.63) | KCNA3SMN1; SMN2HPGDLMNABRD4 | |
| SCHEMBL11387758 | 0.78 | KCNA3 (0.80) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL30783436 | 0.78 | KCNA3 (0.61) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL11379787 | 0.78 | KCNA3 (0.61) | KCNA3SMN1; SMN2HPGDLMNAHTT | |
| SCHEMBL25493370 | 0.77 | KCNA3 (0.78) | KCNA3SMN1; SMN2HPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273930-A | INTERMEDIATES FOR THE 4-ALKOXY ANTIALLERGENS | SANDOZ, INC. (US) | 1981-06-16 | — | — | US | disclosed |
| US-4190659-A | ANTIALLERGENS, ANTIHISTAMINES | SANDOZ, INC. (US) | 1980-02-26 | — | — | US | disclosed |
| US-4032528-A | DEPRESSANTS | SANDOZ, INC. (US) | 1977-06-28 | — | — | US | disclosed |