Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | NQO2 | P16083 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379787 | 1.00 | KCNA3 (0.61) | KCNA3KDM4ENQO2HSD17B10SMN1; SMN2 | |
| SCHEMBL1685959 | 0.81 | KCNA3 (0.57) | KCNA3KDM4ENQO2HSD17B10SMN1; SMN2 | |
| SCHEMBL11375444 | 0.81 | KCNA3 (0.69) | KCNA3KDM4ENQO2HSD17B10SMN1; SMN2 | |
| SCHEMBL29206051 | 0.80 | KCNA3 (0.56) | KCNA3KDM4ENQO2HSD17B10SMN1; SMN2 | |
| SCHEMBL11389662 | 0.79 | KCNA3 (0.74) | KCNA3SMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL17576252 | 0.79 | KDM4E (0.49) | KCNA3KDM4ENQO2HSD17B10SMN1; SMN2 | |
| SCHEMBL12002308 | 0.78 | ALDH1A1 (0.66) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL19330830 | 0.78 | MAPT (0.55) | KDM4ENQO2HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL18026627 | 0.78 | KCNA3 (0.64) | KCNA3KDM4ENQO2HSD17B10SMN1; SMN2 | |
| SCHEMBL2797897 | 0.78 | ALDH1A1 (0.51) | KDM4ESMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624043-A | Preparation method of quinolinone compound | 安徽中医药大学 | 2024-03-01 | — | — | CN | disclosed |