SCHEMBL1138567

SCHEMBL1138567

CC(=O)OC1CC(C)(C)N(OC(C)=O)C(C)(C)C1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.63
TSHR P16473 2/20 0.63
ALDH1A1 P00352 1/20 0.60
ESR1 P03372 1/20 0.60
HSD17B10 Q99714 1/20 0.60
GAA P10253 2/20 0.49
MEN1 O00255 2/20 0.49
CHRM2 P08172 5/20 0.35
CHRM1 P11229 3/20 0.35
CHRM4 P08173 2/20 0.35
CHRM5 P08912 2/20 0.35
CHRM3 P20309 2/20 0.35
HTT P42858 1/20 0.34
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12921994 0.91 TSHR (0.61) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9440230 0.86 TSHR (0.57) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL1139067 0.85 TSHR (0.50) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL5573455 0.85 KMT2A (0.55) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL987544 0.85 TSHR (0.55) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL4325339 0.85 TSHR (0.55) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL13957191 0.84 TSHR (0.56) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL13110328 0.84 TSHR (0.56) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9400301 0.83 TSHR (0.55) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9440185 0.83 TSHR (0.55) KMT2ATSHRALDH1A1ESR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 EP claimed
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
EP-2699727-B1 METHOD OF DYEING POLYESTER HUNTSMAN ADV MAT SWITZERLAND (CH) 2014-11-19 EP disclosed
EP-2699727-A1 METHOD OF DYEING POLYESTER Huntsman Advanced Materials (Switzerland) GmbH (CH) 2014-02-26 EP disclosed
US-20140041134-A1 Method of Dyeing Polyester HUNTSMAN INTERNATIONAL LLC (US) 2014-02-13 US disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
WO-2012143167-A1 METHOD OF DYEING POLYESTER HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2012-10-26 WO disclosed
US-8168725-B2 Degradation of polypropylene with hydroxylamine ester compositions BASF SE (DE) 2012-05-01 US disclosed
EP-1282630-A1 HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS Ciba SC Holding AG (CH) 2003-02-12 EP disclosed
WO-2001090113-A1 HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-11-29 WO disclosed
EP-1132085-A1 DRUGS AND REAGENTS CONTAINING N-ACYLOXYLATED CYCLOALKYL COMPOUNDS AS THE ACTIVE INGREDIENT DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) 2001-09-12 EP disclosed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 EP disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 EP disclosed
US-4130710-A POLYOLEFIN STABILIZERS CIBA-GEIGY CORPORATION (US) 1978-12-19 US disclosed