Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701767 | 0.90 | TSHR (0.43) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL7795589 | 0.86 | ALDH1A1 (0.42) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL9350754 | 0.84 | TSHR (0.38) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1138567 | 0.83 | KMT2A (0.63) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL12921994 | 0.82 | TSHR (0.61) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL9576921 | 0.81 | TSHR (0.35) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1053833 | 0.80 | GAA (0.44) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL3191892 | 0.80 | TSHR (0.33) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL69507 | 0.80 | TSHR (0.33) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL25701766 | 0.79 | TSHR (0.35) | TSHRKMT2AALDH1A1ESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5300647-A | Light stabilizers for polyolefins, other polymers | CIBA-GEIGY CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0309400-B1 | N-acyloxy hindered amine stabilizers | CIBA GEIGY AG (CH) | 1994-03-02 | — | — | EP | disclosed |
| EP-0309400-A2 | N-acyloxy hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |