Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 17/20 | 0.46 |
| ▸ | CA1 | P00915 | 16/20 | 0.46 |
| ▸ | CA12 | O43570 | 14/20 | 0.46 |
| ▸ | CA9 | Q16790 | 12/20 | 0.46 |
| ▸ | CA7 | P43166 | 12/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 12/20 | 0.46 |
| ▸ | CA3 | P07451 | 11/20 | 0.46 |
| ▸ | CA6 | P23280 | 11/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 11/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 10/20 | 0.46 |
| ▸ | CA5A | P35218 | 9/20 | 0.46 |
| ▸ | CA4 | P22748 | 6/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788977 | 0.84 | CISD1 (0.53) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL11370788 | 0.81 | CA2 (0.42) | CA2CA1CA12CA9CA7 | |
| SCHEMBL11796619 | 0.78 | CISD1 (0.49) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL11377930 | 0.75 | CISD1 (0.46) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL11784489 | 0.74 | CA2 (0.47) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL11802086 | 0.74 | CISD1 (0.45) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL21436395 | 0.73 | CISD1 (0.46) | CISD1CA2CA1CA12CA9 | |
| Bromide SCHEMBL11366999 | 0.73 | CA2 (0.47) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL22922714 | 0.72 | CISD1 (0.50) | CISD1CA2CA1CA12CA9 | |
| SCHEMBL11790004 | 0.72 | CA2 (0.52) | CISD1CA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247550-A | Compositions and methods for the treatment of hypertension or oedemas | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1981-01-27 | — | — | US | disclosed |