Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.63 |
| ▸ | MAOB | P27338 | 8/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390499 | 0.87 | CYP19A1 (0.57) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL9464541 | 0.81 | CYP19A1 (0.68) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL23778031 | 0.79 | KDM4E (0.47) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL28118963 | 0.79 | CYP19A1 (0.66) | CYP19A1MAOBCYP3A4ABCB1AR | |
| Liquiritigenin Dimethyl Ether SCHEMBL13394438 | 0.77 | CYP19A1 (1.00) | CYP19A1MAOBCYP3A4ABCB1AR | |
| SCHEMBL11377697 | 0.77 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4 | |
| Liquiritigenin Dimethyl Ether SCHEMBL3303937 | 0.77 | CYP19A1 (1.00) | CYP19A1MAOBCYP3A4ABCB1AR | |
| SCHEMBL11391160 | 0.77 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL17708866 | 0.77 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL1895399 | 0.76 | MAOB (1.00) | CYP19A1MAOBCYP3A4ABCB1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4261988-A | ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-14 | — | — | US | disclosed |