Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.66 |
| ▸ | MAOB | P27338 | 8/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28118581 | 0.88 | ABCB1 (0.64) | CYP19A1MAOBCYP3A4ABCB1AR | |
| SCHEMBL9464541 | 0.83 | CYP19A1 (0.68) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL11387809 | 0.79 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4ABCB1AR | |
| SCHEMBL17708866 | 0.79 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4 | |
| Liquiritigenin Dimethyl Ether SCHEMBL13394438 | 0.79 | CYP19A1 (1.00) | CYP19A1MAOBCYP3A4ABCB1AR | |
| Liquiritigenin Dimethyl Ether SCHEMBL3303937 | 0.79 | CYP19A1 (1.00) | CYP19A1MAOBCYP3A4ABCB1AR | |
| SCHEMBL11391160 | 0.79 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL11377697 | 0.79 | CYP19A1 (0.63) | CYP19A1MAOBCYP3A4 | |
| SCHEMBL131515 | 0.78 | MAOB (1.00) | CYP19A1MAOBCYP3A4ABCB1AR | |
| SCHEMBL1895399 | 0.78 | MAOB (1.00) | CYP19A1MAOBCYP3A4ABCB1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397381-B | 2- alkoxy chromone 9 oxime derivate and the preparation method and application thereof | 苏州大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-106397381-A | 2-alkoxy chromone oxime derivative and preparation method and application thereof | 苏州大学 | 2017-02-15 | — | — | CN | disclosed |