SCHEMBL11388252

SCHEMBL11388252

O=C(O)COC(CC(=O)O)C(=O)O.[CaH2]

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 1/20 0.35
CTH P32929 1/20 0.35
CBS P35520 1/20 0.35
THPO P40225 1/20 0.35
FOLH1 Q04609 2/20 0.33
THRB P10828 1/20 0.33
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38290 0.98 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL10710195 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11293617 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL616354 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
Ammonia Solution, Strong SCHEMBL11291766 0.95 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11150705 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL5681308 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11687090 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
Ammonia Solution, Strong SCHEMBL11291772 0.95 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11687100 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE30755-E PREFERENTIAL REACTION OF AN ALKALI CARBONATE AND THE IMPURE ZINC OR ALKALINE SALTS; STOICHIOMETRY ETHYL CORPORATION (US) 1981-09-29 US disclosed
US-3948985-A FROM MALEIC AND GLYCOLIC ACID FMC CORPORATION (US) 1976-04-06 US disclosed