SCHEMBL616354

SCHEMBL616354

O=C(O)COC(CC(=O)O)C(=O)O.[NaH].[NaH].[NaH]

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.36
TSHR P16473 1/20 0.35
CTH P32929 1/20 0.35
CBS P35520 1/20 0.35
THPO P40225 1/20 0.35
FOLH1 Q04609 2/20 0.33
THRB P10828 1/20 0.33
GABRR1 P24046 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11687100 1.00 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL5681308 1.00 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11687090 1.00 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH
Water SCHEMBL11512960 0.98 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11140412 0.98 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6TSHRCTH
Water SCHEMBL11782796 0.98 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11143922 0.98 TDP1 (0.39) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL38290 0.98 TDP1 (0.42) TDP1SMN1; SMN2SLC22A6TSHRCTH
Ammonia Solution, Strong SCHEMBL11291766 0.95 TDP1 (0.46) TDP1SMN1; SMN2SLC22A6TSHRCTH
SCHEMBL11150705 0.95 TDP1 (0.40) TDP1SMN1; SMN2SLC22A6TSHRCTH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704222-B1 In vivo degradable medical device, composition and method for its production and process for its decomposition BOSTON SCIENT LTD (BB) 2002-11-06 EP claimed
EP-0645150-B1 Medical devices subject to triggered disintegration BOSTON SCIENT LTD (BB) 2001-11-28 EP claimed
US-6096018-A Medical treatment utilizing ionically crosslinked medical devices SCIMED LIFE SYSTEMS, INC. (US) 2000-08-01 US claimed
US-5820608-A Method for in vivo chemically triggered disintegration of medical device HERCULES INCORPORATED (US) 1998-10-13 US claimed
US-5531716-A Medical devices subject to triggered disintegration HERCULES INCORPORATED (US) 1996-07-02 US claimed
US-5531735-A Medical devices containing triggerable disintegration agents HERCULES INCORPORATED (US) 1996-07-02 US claimed
EP-0704222-A1 In vivo degradable medical device, composition and method for its production and process for its decomposition HERCULES INCORPORATED (US) 1996-04-03 EP claimed
EP-0645150-A1 Medical devices subject to triggered disintegration HERCULES INCORPORATED (US) 1995-03-29 EP claimed
US-4137260-A SEEDING WITH TETRAHYDRATE OR PENTAHYDRATE CRYSTALS ETHYL CORPORATION (US) 1979-01-30 US claimed
US-3990983-A CHLORINATED TRISODIUM PHOSPHATE, TRISODIUM CARBOXYMETHYLOXYSUCCINATE, SODIUM SULFATE, SODIUM SILICATE LEVER BROTHERS COMPANY (US) 1976-11-09 US claimed
EP-4110411-B1 SPRAYABLE STIMULI-RESPONSIVE MICRO-HYDROGELS FOR ADHESION PREVENTION AND ENHANCED TISSUE HEALING Texas Medical Center (US) 2026-04-08 EP disclosed
US-20240139387-A1 SPRAYABLE STIMULI-RESPONSIVE MICRO-HYDROGELS FOR ADHESION PREVENTION AND ENHANCED TISSUE HEALING Texas Medical Center (US) 2024-05-02 US disclosed
US-11925731-B2 Sprayable stimuli-responsive micro-hydrogels for adhesion prevention and enhanced tissue healing Texas Medical Center (US) 2024-03-12 US disclosed
EP-4110411-A1 SPRAYABLE STIMULI-RESPONSIVE MICRO-HYDROGELS FOR ADHESION PREVENTION AND ENHANCED TISSUE HEALING Texas Medical Center (US) 2023-01-04 EP disclosed
US-20220401631-A1 SPRAYABLE STIMULI-RESPONSIVE MICRO-HYDROGELS FOR ADHESION PREVENTION AND ENHANCED TISSUE HEALING Texas Medical Center 2022-12-22 US disclosed
US-3943165-A DETERGENT SOLVENTS, PLASTICIZERS LEVER BROTHERS COMPANY (US) 1976-03-09 US disclosed
US-3941710-A Phosphate - free dishwashing compositions containing an alkyl polyether carboxylate surfactant LEVER BROTHERS COMPANY (US) 1976-03-02 US disclosed
US-3940433-A SURFACTANTS, DETERGENTS LEVER BROTHERS COMPANY (US) 1976-02-24 US disclosed
US-3936448-A DETERGENTS, BUILDERS LEVER BROTHERS COMPANY (US) 1976-02-03 US disclosed
US-3935206-A Sulfosuccinate derivatives as detergent builders LEVER BROTHERS COMPANY (US) 1976-01-27 US disclosed