Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.74 |
| ▸ | PPARA | Q07869 | 8/20 | 0.74 |
| ▸ | FABP2 | P12104 | 2/20 | 0.74 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377777 | 0.90 | PPARG (0.58) | PPARGPPARAFABP2SLC22A12MEN1 | |
| SCHEMBL11401778 | 0.90 | PPARG (0.58) | PPARGPPARAFABP2SLC22A12MEN1 | |
| SCHEMBL11399949 | 0.87 | PPARG (0.57) | PPARGPPARAFABP2SLC22A12LMNA | |
| SCHEMBL11410847 | 0.86 | STS (0.58) | PPARGPPARAFABP2SLC22A12MEN1 | |
| SCHEMBL21378829 | 0.86 | PPARG (0.74) | PPARGPPARAFABP2SLC22A12MEN1 | |
| Fenofibric Acid SCHEMBL16377 | 0.85 | PPARA (1.00) | PPARGPPARAFABP2SLC22A12MEN1 | |
| Fenofibric Acid SCHEMBL10967778 | 0.84 | PPARA (0.97) | PPARGPPARAFABP2SLC22A12MEN1 | |
| Fenofibric Acid SCHEMBL28478335 | 0.84 | PPARA (0.97) | PPARGPPARAFABP2SLC22A12MEN1 | |
| SCHEMBL11379652 | 0.84 | SRD5A2 (0.52) | PPARGPPARAFABP2SLC22A12PPARD | |
| SCHEMBL11400205 | 0.83 | POLB (0.52) | PPARGPPARAFABP2SLC22A12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287209-A | USEFUL AS METABOLIC REGULATORS, AND HERBICIDES | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1981-09-01 | — | — | US | disclosed |
| US-4146385-A | METABOLIC REGULATORS, CARDIOVASCULAR AGENTS, HERBICIDES | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. (FR) | 1979-03-27 | — | — | US | disclosed |