Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.49 |
| ▸ | CES1 | P23141 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184026 | 0.87 | DHODH (0.50) | CYP11B1CYP11B2CES2CES1GAA | |
| SCHEMBL184027 | 0.87 | DHODH (0.50) | CYP11B1CYP11B2CES2CES1GAA | |
| SCHEMBL18017493 | 0.87 | DHODH (0.50) | CYP11B1CYP11B2CES2CES1GAA | |
| SCHEMBL16613212 | 0.85 | ALDH1A1 (0.49) | CYP11B1CYP11B2GAAALDH1A1KMT2A | |
| SCHEMBL16597890 | 0.85 | ALDH1A1 (0.49) | CYP11B1CYP11B2GAAALDH1A1KMT2A | |
| SCHEMBL16597891 | 0.85 | ALDH1A1 (0.49) | CYP11B1CYP11B2GAAALDH1A1KMT2A | |
| SCHEMBL3565354 | 0.84 | CYP11B1 (0.54) | CYP11B1CYP11B2CES2CES1GAA | |
| SCHEMBL3412173 | 0.84 | CYP11B1 (0.54) | CYP11B1CYP11B2CES2CES1GAA | |
| SCHEMBL29254517 | 0.84 | MAPT (0.56) | CES2CES1GAAALDH1A1KMT2A | |
| SCHEMBL3412170 | 0.84 | CYP11B1 (0.54) | CYP11B1CYP11B2CES2CES1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243406-A | REDUCING INJURIES TO CROP PLANTS WHEN USING AN ALPHA-HALOACETANILIDE AS A HERBICIDE | MONSANTO COMPANY (US) | 1981-01-06 | — | — | US | disclosed |