Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11871667 | 0.99 | MAPT (0.50) | MAPTTHRBTP53HPGDHRH1 | |
| SCHEMBL11393400 | 0.91 | CHRM2 (0.52) | MAPTTHRBTP53HPGDHRH1 | |
| SCHEMBL11876008 | 0.91 | CHRM2 (0.52) | MAPTTHRBTP53HPGDHRH1 | |
| Hydrochloric Acid SCHEMBL11861430 | 0.90 | CHRM2 (0.51) | MAPTTHRBTP53HPGDHRH1 | |
| Hydrochloric Acid SCHEMBL11866707 | 0.90 | CHRM2 (0.51) | MAPTTHRBTP53HPGDHRH1 | |
| SCHEMBL11389479 | 0.89 | HRH1 (0.47) | MAPTTHRBTP53HPGDHRH1 | |
| Hydrochloric Acid SCHEMBL11868987 | 0.88 | HRH1 (0.46) | MAPTTHRBTP53HPGDHRH1 | |
| SCHEMBL11397624 | 0.84 | SIGMAR1 (0.42) | MAPTTHRBTP53HPGDSLC6A2 | |
| SCHEMBL11388761 | 0.81 | MAPT (0.50) | MAPTTHRBTP53HPGDHRH1 | |
| Hydrochloric Acid SCHEMBL11869651 | 0.80 | MAPT (0.49) | MAPTTHRBTP53HPGDHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273772-A | Method of reducing gastric secretion | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1981-06-16 | — | — | US | disclosed |