Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 5/20 | 0.62 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | RIOX2 | Q8IUF8 | 3/20 | 0.62 |
| ▸ | P4HTM | Q9NXG6 | 5/20 | 0.58 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.57 |
| ▸ | KDM6B | O15054 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398234 | 0.82 | P4HTM (0.78) | ASPHKDM8KDM4ERIOX2P4HTM | |
| SCHEMBL22050225 | 0.81 | P4HTM (0.58) | KDM4EP4HTMKDM6BKDM4CKMT2A | |
| SCHEMBL13954312 | 0.77 | P4HTM (0.61) | KDM4EP4HTMKDM6BKDM4CKMT2A | |
| SCHEMBL11258302 | 0.77 | NPC1 (0.55) | ASPHKDM8KDM4EKDM6BKDM4C | |
| SCHEMBL26049197 | 0.75 | P4HTM (0.62) | KDM4EP4HTMALDH1A1L3MBTL1 | |
| SCHEMBL25745959 | 0.74 | NAMPT (0.68) | KDM4ENAMPTHIF1AALDH1A1CYP1A2 | |
| SCHEMBL11396052 | 0.74 | P4HTM (1.00) | ASPHKDM8KDM4ERIOX2P4HTM | |
| SCHEMBL30112058 | 0.73 | P4HTM (0.60) | KDM4EP4HTMKMT2AHIF1AMEN1 | |
| SCHEMBL18405340 | 0.73 | P4HTM (0.60) | KDM4EP4HTMKMT2AHIF1AMEN1 | |
| SCHEMBL797424 | 0.73 | P4HTM (0.60) | KDM4EP4HTMALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273779-A | Treating hypertension with substituted-5-amino-2-pyridinecarboxylic acids | CIBA-GEIGY CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |