Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11392129 | 0.88 | MCL1 (0.52) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11394150 | 0.85 | BCL2L1 (0.49) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11400179 | 0.84 | MCL1 (0.53) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL5023231 | 0.78 | MCL1 (0.77) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11393871 | 0.78 | MCL1 (0.47) | MCL1RAB9ANPC1MAPTLMNA | |
| SCHEMBL11398642 | 0.75 | MCL1 (0.61) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11398641 | 0.72 | MCL1 (0.58) | MCL1BCL2L1RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL11400183 | 0.72 | MCL1 (0.53) | MCL1BCL2L1RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL11394155 | 0.71 | BCL2L1 (0.47) | MCL1BCL2L1RAB9ANPC1MAPT | |
| SCHEMBL11393470 | 0.70 | RXFP1 (0.48) | MCL1RAB9ANPC1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259336-A | ANALGESIC, ANTIPYRETIC, ANTITHROMBOTIC, ANTIPHLOGISTIC | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-31 | — | — | US | disclosed |
| EP-0009142-A1 | 4-Hydroxy-2H(1)benzothieno(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxide derivatives and salts thereof, their use and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1980-04-02 | — | — | EP | disclosed |