Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27030841 | 0.87 | MCL1 (0.60) | MCL1HDAC1HDAC8HDAC6LIMK1 | |
| Hydrochloric Acid SCHEMBL11393877 | 0.87 | MCL1 (0.47) | MCL1HDAC1HDAC8HDAC6LIMK1 | |
| SCHEMBL10969896 | 0.81 | LMNA (0.61) | MCL1HDAC1HDAC8HDAC6MAPT | |
| SCHEMBL11400179 | 0.80 | MCL1 (0.53) | MCL1MAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL11392124 | 0.78 | MCL1 (0.52) | MCL1MAPTALDH1A1GAALMNA | |
| SCHEMBL64428 | 0.75 | MCL1 (0.73) | MCL1HDAC1HDAC8HDAC6OGG1 | |
| SCHEMBL27629193 | 0.75 | MCL1 (0.53) | MCL1HDAC1HDAC8HDAC6LIMK1 | |
| SCHEMBL30980091 | 0.74 | PTGS2 (0.56) | MCL1HDAC1HDAC8HDAC6LIMK1 | |
| SCHEMBL2610245 | 0.74 | RXFP1 (0.59) | MCL1HDAC1HDAC8HDAC6LIMK1 | |
| SCHEMBL6957613 | 0.74 | ACLY (0.44) | MCL1MAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259336-A | ANALGESIC, ANTIPYRETIC, ANTITHROMBOTIC, ANTIPHLOGISTIC | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-31 | — | — | US | disclosed |
| EP-0009142-A1 | 4-Hydroxy-2H(1)benzothieno(2,3-e)-1,2-thiazine-3-carboxamide-1,1-dioxide derivatives and salts thereof, their use and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1980-04-02 | — | — | EP | disclosed |