Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL326803 | 0.82 | NQO1 (0.52) | KDM4EMTNR1AMTNR1BEPHX1TSHR | |
| SCHEMBL21605387 | 0.82 | KDM4E (0.50) | KDM4EMTNR1AEPHX1SQSTM1KEAP1 | |
| SCHEMBL19289929 | 0.82 | KDM4E (0.49) | KDM4ESQSTM1KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL10725887 | 0.80 | KDM4E (0.47) | KDM4ESQSTM1KEAP1NFE2L2TSHR | |
| SCHEMBL11396070 | 0.79 | SMN1; SMN2 (0.50) | KDM4EEPHX1HSD17B10L3MBTL1LMNA | |
| SCHEMBL3742706 | 0.79 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BEPHX1TSHR | |
| SCHEMBL7666973 | 0.79 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BEPHX1TSHR | |
| SCHEMBL30072284 | 0.79 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BEPHX1TSHR | |
| SCHEMBL28747044 | 0.79 | KDM4E (0.50) | KDM4EMTNR1ASQSTM1KEAP1NFE2L2 | |
| SCHEMBL11451411 | 0.78 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BEPHX1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288608-A | Synthesis of anthracyclines | RESEARCH CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4196127-A | INTERMEDIATES FOR DAUNOMYCIN ANTIBIOTICS, ANTITUMOR | RESEARCH CORPORATION (US) | 1980-04-01 | — | — | US | disclosed |
| EP-0007400-A1 | Anthracene derivatives useful as intermediates in the preparation of daunomycinones | Research Corporation (US) | 1980-02-06 | — | — | EP | disclosed |