Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30072284 | 1.00 | KDM4E (0.49) | KDM4ENQO1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL16950704 | 0.89 | MTNR1A (0.56) | KDM4EMTNR1AMTNR1BALDH1A1HPGD | |
| SCHEMBL16959703 | 0.89 | HSD17B10 (0.47) | KDM4ENQO1HPGDTSHRHTT | |
| SCHEMBL6784748 | 0.85 | KDM4E (0.53) | KDM4ENQO1ALDH1A1HPGDEPHX1 | |
| SCHEMBL16960502 | 0.84 | ALDH1A1 (0.41) | KDM4ENQO1ALDH1A1HPGDEPHX1 | |
| SCHEMBL326803 | 0.84 | NQO1 (0.52) | KDM4ENQO1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL16957460 | 0.83 | L3MBTL1 (0.44) | KDM4ENQO1ALDH1A1HPGDEPHX1 | |
| SCHEMBL16951352 | 0.83 | MEN1 (0.44) | KDM4ENQO1ALDH1A1HPGDEPHX1 | |
| SCHEMBL16961968 | 0.83 | TACR1 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL10673171 | 0.81 | NQO1 (0.48) | KDM4ENQO1MTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349027-B | A kind of preparation method of high-order column aromatic hydrocarbons | 浙江大学 | 2019-03-26 | — | — | CN | claimed |
| CN-106349027-A | Preparation method of high-order column aromatic hydrocarbon | 浙江大学 | 2017-01-25 | — | — | CN | claimed |
| CN-115337913-B | Catechu [9] arene, and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2024-03-22 | — | — | CN | disclosed |
| CN-115337913-A | Catechu [9] arene and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2022-11-15 | — | — | CN | disclosed |
| US-11289238-B2 | Compositions for the filling of high aspect ratio vertical interconnect access (VIA) holes | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) | 2022-03-29 | — | — | US | disclosed |
| US-20210174983-A1 | COMPOSITIONS FOR THE FILLING OF HIGH ASPECT RATIO VERTICAL INTERCONNECT ACCESS (VIA) HOLES | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC | 2021-06-10 | — | — | US | disclosed |
| WO-2021112933-A1 | COMPOSITIONS FOR THE FILLING OF HIGH ASPECT RATIO VERTICAL INTERCONNECT ACCESS (VIA) HOLES | HERAEUS PRECIOUS METALS NORTH AMERICA CONSHOHOCKEN LLC (US) | 2021-06-10 | — | — | WO | disclosed |
| CN-106349027-A | Preparation method of high-order column aromatic hydrocarbon | 浙江大学 | 2017-01-25 | — | — | CN | disclosed |
| US-8273890-B2 | Thiophene-imidazopyridines | 4SC AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-20100278833-A1 | THIOPHENE-IMIDAZOPYRIDINES | 4SC AG (DE) | 2010-11-04 | — | — | US | disclosed |
| WO-2009003911-A1 | THIOPHENE-IMIDAZOPYRIDINES | 4SC AG (DE) | 2009-01-08 | — | — | WO | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278833-A1 | THIOPHENE-IMIDAZOPYRIDINES | PIKFYVE, PIP4K2B, PIP5K1B | KDM4E 1387/4885NQO1 4132/4885MTNR1A 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.