Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399494 | 0.92 | HTT (0.46) | HTTALDH1A1HSD17B10MAPK1KMT2A | |
| SCHEMBL11395314 | 0.88 | HTT (0.50) | HTTALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL8019096 | 0.77 | HTT (0.42) | HTTHSD17B10MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL10974157 | 0.75 | MAPK1 (0.47) | HTTALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL829121 | 0.74 | EGLN3 (0.44) | ALDH1A1HPGDMAPK1HSD11B1 | |
| SCHEMBL11397810 | 0.73 | MEN1 (0.43) | ALDH1A1HPGDHSD17B10KMT2ALMNA | |
| SCHEMBL10672406 | 0.73 | HTT (0.36) | HTTALDH1A1HSD17B10MAPK1KMT2A | |
| SCHEMBL2561990 | 0.73 | — | — | |
| SCHEMBL11395318 | 0.73 | FAAH (0.36) | ALDH1A1HPGDMAPK1KMT2ACYP2C19 | |
| SCHEMBL11348337 | 0.73 | CYP1A2 (0.37) | HTTHSD17B10MAPK1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4286089-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |