Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12018103 | 0.91 | MAPT (0.55) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5829506 | 0.84 | MAPT (0.56) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11123380 | 0.82 | CPA1 (0.62) | LMNACPA1ALDH1A1ANPEPERAP2 | |
| SCHEMBL8313296 | 0.82 | CPA1 (0.62) | CPA1ANPEP | |
| SCHEMBL10436410 | 0.81 | CPA1 (0.57) | LMNACPA1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9656917 | 0.81 | EPHX2 (0.51) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9656913 | 0.80 | EPHX2 (0.50) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10747515 | 0.80 | MAPT (0.52) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11829173 | 0.80 | MAPT (0.52) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10521304 | 0.79 | MAPT (0.51) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038046-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-10-21 | — | — | EP | disclosed |