Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823414 | 0.83 | SRR (0.49) | LMNAALDH1A1GAA | |
| SCHEMBL11835523 | 0.83 | TSHR (0.45) | MAPTLMNAKDM4ERAB9AALDH1A1 | |
| SCHEMBL11828776 | 0.82 | HRH2 (0.46) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5829506 | 0.82 | MAPT (0.56) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL12018103 | 0.81 | MAPT (0.55) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11394378 | 0.80 | MAPT (0.54) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL10747515 | 0.78 | MAPT (0.52) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10521304 | 0.77 | MAPT (0.51) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11829788 | 0.76 | PDCD1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL11829659 | 0.76 | MAPT (0.48) | MAPTLMNAKDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |