Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139791 | 1.00 | CTSS (0.39) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1139726 | 0.90 | CTSS (0.39) | CTSSCTSLCTSB | |
| SCHEMBL1139212 | 0.90 | CTSS (0.39) | CTSSCTSLCTSB | |
| SCHEMBL1139136 | 0.87 | CTSS (0.39) | CTSS | |
| SCHEMBL1139330 | 0.87 | CTSS (0.39) | CTSS | |
| SCHEMBL1139047 | 0.86 | CTSS (0.43) | CTSS | |
| SCHEMBL1139534 | 0.86 | CTSS (0.43) | CTSS | |
| SCHEMBL1139215 | 0.85 | GRM2 (0.34) | CTSSCTSLCTSK | |
| SCHEMBL1139350 | 0.85 | GRM2 (0.34) | CTSSCTSLCTSK | |
| SCHEMBL1139634 | 0.85 | CTSS (0.41) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893099-B2 | Cyclopentane derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-02-22 | — | — | US | claimed |
| US-7893099-B2 | Cyclopentane derivatives | HOFFMAN-LA ROCHE INC. (US) | 2011-02-22 | — | — | US | disclosed |