SCHEMBL11396752

SCHEMBL11396752

CC(O)(C(=O)c1ccccc1)c1ccccc1.CN1CCN(CCOCCN2CCN(C)CC2)CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM5 P08912 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
GAA P10253 2/20 0.48
HRH3 Q9Y5N1 2/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
POLB P06746 3/20 0.43
KDM4E B2RXH2 4/20 0.43
MAPT P10636 1/20 0.43
RAD52 P43351 1/20 0.43
DRD3 P35462 1/20 0.43
RECQL P46063 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KCNA5 P22460 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11406208 0.88 ALDH1A1 (0.50) ALDH1A1MEN1KMT2APOLBKDM4E
SCHEMBL11293625 0.80 ALDH1A1 (0.57) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL11399934 0.77 CES1 (0.45) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL58021 0.76 CES1 (0.55) ALDH1A1KMT2AMAPT
Ether SCHEMBL5570218 0.75 CES1 (0.49) ALDH1A1MEN1KMT2APOLBMAPT
Methoxymethane SCHEMBL7788767 0.74 CES1 (0.59) ALDH1A1KMT2AMAPT
SCHEMBL11661275 0.74 CES1 (0.50) ALDH1A1KMT2AMAPT
SCHEMBL2663560 0.73 HRH3 (0.71) ALDH1A1MEN1KMT2AGAAHRH3
SCHEMBL30712480 0.72 ALDH1A1 (0.64) ALDH1A1CHRM2CHRM4CHRM5CHRM1
Dimethylamine SCHEMBL6328605 0.71 CES1 (0.50) ALDH1A1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4271294-A PHOTOINITIATORS CIBA-GEIGY CORPORATION (US) 1981-06-02 US disclosed